Place the analyte in an Erlenmeyer flask (a conical flat-bottomed laboratory flask with a narrow neck). Place the titrant in a burette (a graduated glass tube with a tap at one end).

Add the titrant to the analyte until the endpoint is reached. This is often indicated by a color change, for example by adding a few drop of phenolphthalein, a commonly used acid‑base indicator, which changes from pink in alkali to colorless in acid.

Use the titration formula. If the titrant and analyte have a 1:1 mole ratio, the formula is molarity (M) of the acid x volume (V) of the acid = molarity (M) of the base x volume (V) of the base. (Molarity is the concentration of a solution expressed as the number of moles of solute per litre of solution.)

If the ratio is not 1:1, use a modified version of the formula. For example, if 35 ml of 1.25 M hydrochloric acid (HCI) is needed to titrate a 25 ml solution of sodium hydroxide (NaOH) to the equivalence point, you can work out the concentration of NaOH using the 1:1 ratio formula, because hydrochloric acid and sodium hydroxide have a 1:1 mole ratio (one mole of HCl reacts with one mole of NaOH).

Multiply the molarity of the acid by the volume of the acid (1.25 x 35). Then take this answer (43.75) and divide it by the volume of the base (25). The answer is 1.75 M, which is the molarity of the base.