All of the Information Needed to Make Proteins Is Coded in DNA By What?

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DNA is a long polymer molecule. A polymer is a big molecule built from many identical or nearly identical parts. In the case of DNA, the nearly identical parts are molecules called nuclear bases: adenine, thymine, cytosine and guanine. The four bases are often abbreviated A, T, C and G. The order of the bases -- the specific order of A, T, C and G -- contains all the information needed to build proteins.

DNA and Proteins

DNA is a relatively simple molecule compared to the proteins in the cell. So one question scientists had was how a simple molecule could control the construction of the more complex ones. One example of the confusion: DNA is built from pretty much only four components, the nuclear bases, while proteins are built from 20 different amino acids. The answer was in the order of the bases.

The Genetic Code

If every nuclear base corresponded to one amino acid, proteins could only have four different amino acids. If it took two bases to correspond to the amino acids -- AA, AT, AG and so forth -- there could only be a maximum of 16 different amino acids. The answer is that it takes three bases together to control the assembly of an amino acid onto a protein. The three letter codes are called "triplets" or "codons."

References

About the Author

First published in 1998, Richard Gaughan has contributed to publications such as "Photonics Spectra," "The Scientist" and other magazines. He is the author of "Accidental Genius: The World's Greatest By-Chance Discoveries." Gaughan holds a Bachelor of Science in physics from the University of Chicago.

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  • Thomas Northcut/Digital Vision/Getty Images

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