Is There an Easy Way to Remember the Glycolysis Cycle?

By Donna M. Peterson
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One way to remember the glycolysis cycle is to remember the literal meanings of the word's roots. "Glyco" is from the Greek root, "gleukos," meaning "sweet." The Latin root, "lysis," means "to break apart." Glycolysis is the process of breaking apart sugar molecules to produce energy. Whether a single bacterium, or part of a human organ, the biggest need of any cell is an immediate source of energy. According to Michael Muller of the University of Illinois at Chicago, all living things produce adenosine triphosphate (ATP), the main energy carrier between reaction sites in cells, by releasing the energy stored in sugars.

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Break down the glucose molecule. Enzymes, proteins that speed a reaction without being changed by it, convert a molecule of glucose with six carbon atoms into two molecules of phosphoglyceraldehyde (PGAL) and three carbon molecules. PGAL is a middle stage in the glycolysis cycle.

Change two PGAL and three carbon molecules into two pyruvate molecules, each with six atoms of carbon. Pyruvate is an organic compound. This conversion creates two ATP molecules. If this is an anaerobic pathway, such as that used in fermentation, the process is complete. An aerobic pathway, where oxygen is used to produce even more energy, requires Step 3.

Begin the Krebs cycle. This process takes place in the mitochondria of the cell, and occurs after the end of glycolysis. In the Krebs Cycle, pyruvate is fully broken down to carbon dioxide, water, two ATP molecules and many coenzymes, or enzyme helpers.

Flow through the Electron Transport Chain. In this stage, electrons pass through arrays of enzymes that accept and give up electrons in sequence, releasing the energy of the electrons in small increments. At the end of this sequence the cell has produced 36 molecules of ATP, rather than the two at the end of glycolysis.

About the Author

Donna M. Peterson has written professionally since 1992. Her articles and columns have appeared in "The Roseburg Beacon," "The Monticello Times" and "The Annandale Advocate." An expert photographer and graphic aritst, Peterson holds an Associate of Applied Science in broadcasting production from Lane Community College, and studies sociology at the University of Oregon.